Bone cancer is a rare but aggressive malignancy that affects both children and adults. It may start in the bone (primary bone cancer) or spread to the bone from other parts of the body (metastatic bone cancer). The most common types include osteosarcoma, chondrosarcoma, and Ewing sarcoma. India has become a preferred global destination for bone cancer treatment due to its cost-effective pricing, access to world-class oncologists like Dr. Ankur Bahl, and advanced infrastructure. The total cost of bone cancer treatment in India typically ranges between USD 10,000 to 15,000, which includes surgery, chemotherapy, radiation therapy, diagnostics, and post-treatment rehabilitation. In comparison, the same treatment can cost up to USD 80,000 to 150,000 in countries like the USA. Indian hospitals offer cutting-edge solutions, including limb-salvage surgeries, targeted therapy, immunotherapy, and robotic-assisted interventions, all at a fraction of the cost
What is Bone Cancer and Its Treatment?
Bone cancer is a rare type of cancer that begins in the cells of the bone. It occurs when abnormal cells in the bone grow uncontrollably, forming a tumor. These tumors can be benign (non-cancerous) or malignant (cancerous). Malignant bone cancer can destroy normal bone tissue and may spread to other parts of the body.
What are the Types of Bone Cancer Treated in India?
India offers comprehensive diagnosis and treatment for all major types of primary bone cancers and some rare bone tumors. Each type requires a distinct treatment approach based on its location, grade, and stage. The following are the main types of bone cancer commonly treated by oncologists in India:
1. Osteosarcoma
- Description: The most common type of bone cancer, typically affecting children, teenagers, and young adults.
- Location: Often begins in the long bones—especially around the knee and upper arm.
- Treatment in India: Multimodal treatment including surgery (limb-salvage or amputation), chemotherapy (pre- and post-operative), and occasional radiation therapy.
2. Ewing Sarcoma
- Description: A highly aggressive cancer that occurs in bones or soft tissue around the bones, most often in children and adolescents.
- Location: Pelvis, femur, ribs, and humerus are common sites.
- Treatment in India: Intensive chemotherapy, followed by surgery and/or radiation therapy. India also offers high-end limb-preserving surgeries and targeted treatments.
3. Chondrosarcoma
- Description: A cancer that originates in cartilage cells. More common in adults over 40.
- Location: Pelvis, femur, humerus, and shoulder.
- Treatment in India: Surgical resection is the mainstay, as this type is typically resistant to chemotherapy and radiation. Advanced orthopedic oncology centers in India provide en bloc resections and endoprosthetic reconstruction.
4. Chordoma
- Description: A slow-growing, rare cancer that occurs along the spine and base of the skull.
- Location: Skull base and sacrum.
- Treatment in India: Specialized neurosurgical resection, often followed by proton beam therapy or high-precision radiation techniques like IMRT or CyberKnife.
5. Malignant Fibrous Histiocytoma (MFH) / Undifferentiated Pleomorphic Sarcoma (UPS) of Bone
- Description: A rare and aggressive cancer that can appear in soft tissues and bones.
- Location: Long bones and pelvis.
- Treatment in India: Wide surgical excision combined with chemotherapy. India has centers that specialize in high-grade sarcoma treatment protocols.
6. Giant Cell Tumor of Bone (Malignant or Aggressive Variant)
- Description: Usually benign but can be aggressive or turn malignant in rare cases.
- Location: Knee, wrist, and spine.
- Treatment in India: Curettage with cementation, wide excision, and targeted therapies like denosumab for unresectable cases.
7. Metastatic Bone Cancer
- Description: Not a primary bone cancer, but a secondary cancer that spreads from other organs (like breast, prostate, or lung) to bones.
- Treatment in India: Focused on palliative care, pain management, and stabilizing bone integrity using radiation, bisphosphonates, or surgical fixation.
How is bone cancer initially diagnosed?
The diagnosis begins with a combination of:
- X-rays and MRI scans to assess the tumor location and size.
- CT scans and PET-CT to detect metastasis.
- Bone biopsy (open or needle) to confirm the cancer type.
- Blood tests, including alkaline phosphatase and LDH levels.
What is the standard treatment protocol for osteosarcoma?
- Neoadjuvant Chemotherapy (before surgery) for 6–8 weeks using drugs like Doxorubicin, Cisplatin, and Methotrexate.
- Surgical resection or limb-salvage surgery depending on tumor location and size.
- Adjuvant Chemotherapy post-surgery to reduce recurrence.
- Follow-up scans and blood tests every 3–6 months.
What surgical options are available for bone cancer in India?
Surgery is the cornerstone of treatment and includes:
- Limb-salvage surgery (preferred over amputation when feasible)
- Amputation in advanced or complex cases
- Endoprosthetic reconstruction to replace resected bone with implants
- Spinal stabilization for vertebral tumors
Is chemotherapy always required for bone cancer?
Not always. Chemotherapy is essential for:
- Osteosarcoma and Ewing sarcoma (both highly chemo-sensitive)
- May not be necessary in chondrosarcoma, which is more resistant.
- Treatment is tailored based on histological subtype and staging.
Is radiation therapy used in bone cancer treatment?
Yes, but selectively:
- Ewing Sarcoma: Very responsive to radiation.
- Osteosarcoma: Less responsive, used when surgery is not possible.
- Techniques include IMRT and Proton Therapy for precision targeting.
What role does targeted therapy or immunotherapy play?
In advanced or metastatic bone cancers:
- Targeted therapies like Pazopanib, Sorafenib (in select sarcomas)
- Immunotherapy: Under clinical trials or for refractory cases
- These are used in combination with palliative care or post-chemotherapy.
What is the protocol for metastatic or relapsed bone cancer?
- High-dose chemotherapy
- Metastasectomy (lung nodule resection)
- Palliative radiotherapy for bone pain
- Bisphosphonates for bone strengthening
- Enrolling in clinical trials if eligible
Bone Cancer Treatment Cost: India vs Turkey vs USA
Treatment Type |
India (USD) |
Turkey (USD) |
USA (USD) |
TURBT Surgery (Tumor Removal) |
$1,500 – $3,000 |
$3,000 – $5,000 |
$8,000 – $15,000
|
Radical Cystectomy |
$4,000 – $6,500 |
$8,000 – $12,000 |
$25,000 – $45,000
|
Chemotherapy (per cycle) |
$700 – $1,500 |
$1,500 – $3,000 |
$10,000 – $50,000
|
Intravesical Therapy (BCG/Drugs) |
$500 – $1,000 |
$1,200 – $2,000 |
$8,000 – $12,000
|
Radiation IGRT |
$6000 |
$15000 |
$30,000 - $50,000
|
Radiation IMRT |
$5000 |
$15000 |
$30,000 - $50,000
|
Radiation V-MAT |
$6500 |
$15000 |
$30,000 - $50,000
|
Immunotherapy (PD-1, per cycle) |
$1,500 – $2,500 |
$2,000 – $5,000 |
$10,000 – $20,000
|
PET-CT Scan |
$300 – $500 |
$500 – $800 |
$3,000 – $6,000 |
HPV Testing & Biopsy |
$100 – $300 |
$300 – $600 |
$1,000 – $2,000 |
Why International Patients Choose India for Bone Cancer Treatment?
- Affordable Pricing
- World-Class Infrastructure
- Experienced Doctors and Surgeons
- Personalized Patient Support
- No Waiting List
- Multilingual Support Teams
What are the Support Services for International Patients in India?
- Medical Visa Assistance
- Airport Pickup & Travel Coordination
- Affordable Accommodation Options
- Dedicated International Patient Desk
- Post-Treatment Online Follow-ups