Pleuropulmonary Blastoma Treatment in India

India provides world-class and compassionate care for Pleuropulmonary Blastoma (PPB) under expert oncologists like Dr. Ankur Bahl, supported by pediatric and thoracic surgical teams. Treatment costs in India range from $6,000 to $18,000 USD, depending on surgery, chemotherapy, and hospital stay. In contrast, treatment in the USA ranges from $120,000 to $250,000, and in Thailand from $35,000 to $60,000. India offers affordable and expert care with international patient support services included.

What is Pleuropulmonary Blastoma (PPB)?

Pleuropulmonary Blastoma (PPB) is a rare and aggressive childhood cancer that originates in the lung or the pleura—the membrane surrounding the lungs. It most commonly affects children under the age of 6. PPB is a type of embryonal tumor and is distinct from adult lung cancers both in cause and behavior.

This cancer is unique in that it may initially present as a benign cystic lesion before evolving into a solid tumor. Early detection and treatment are essential for improving outcomes, especially for Types I and II.

What causes PPB and who is at risk?

The primary known cause of PPB is a genetic mutation in the DICER1 gene, which plays a key role in controlling cell growth and division. Children with this mutation are also at risk for other rare tumors like ovarian Sertoli-Leydig tumors and Wilms' tumor.

Risk factors include:

• Age: Usually diagnosed in children under 6
• Genetics: Family history of DICER1-related conditions
• Previous benign lung cysts: Some cysts progress into PPB

What are the types or stages of PPB?

PPB is classified into three main types based on its progression:

Type I – Purely Cystic:

• Typically seen in infants and toddlers
• Best prognosis with surgery alone
• Often detected during respiratory infections

Type II – Mixed Cystic and Solid:

• Represents a transition phase
• Requires surgery and chemotherapy
• Intermediate risk and progression potential

Type III – Solid:

• Most aggressive form
• Typically presents with large tumor mass
• Requires full multimodal therapy: surgery, chemo, possibly radiation

What are the symptoms of Pleuropulmonary Blastoma?

Symptoms may mimic common respiratory infections or lung diseases, making diagnosis challenging without imaging.

Common Symptoms:

• Persistent cough
• Breathing difficulty or wheezing
• Chest pain or tightness
• Fever and fatigue
• Recurrent lung infections or pneumonia
• Typically seen in infants and toddlers
• Best prognosis with surgery alone
• Often detected during respiratory infections

In some cases, the tumor is discovered incidentally during imaging for unrelated illnesses.

How is PPB diagnosed in India?

Top Indian hospitals use a multi-step approach for accurate and rapid diagnosis of PPB in children.

Diagnostic Process:

• Chest X-ray & CT Scan: Initial imaging to detect mass or cysts
• MRI: To assess soft tissue and spread to nearby areas
• Lung Biopsy: Surgical or needle biopsy for histopathological confirmation
• DICER1 Genetic Testing: For confirmation and family screening
• PET-CT or Bone Scan: To check for metastasis in advanced cases

All tests are completed within 3–5 working days in pediatric oncology centers.

What is the treatment protocol for Pleuropulmonary Blastoma in India?

Treatment in India is multidisciplinary, involving pediatric oncologists, thoracic surgeons, and geneticists. Protocols follow SIOP and COG international guidelines.

Step-by-Step Treatment:

Surgical Resection:

• Lobectomy or segmentectomy depending on tumor size and location
• Minimally invasive approaches used when possible

Chemotherapy:

• Required for Types II and III
• Agents include Ifosfamide, Vincristine, Actinomycin D, and Doxorubicin
• Typically given in 4–6 cycles

Radiation Therapy:

• Rarely used
• Considered in cases of residual or recurrent disease

Post-treatment Monitoring:

• Regular imaging for recurrence
• Lung function tests
• Genetic counseling if DICER1 positive

Continuing with the next sections of your detailed article on Pleuropulmonary Blastoma (PPB) Treatment in India:

Why should international patients choose India for PPB treatment?

India is increasingly recognized for offering high-quality, affordable pediatric oncology care, including the treatment of rare cancers like Pleuropulmonary Blastoma.

Benefits for International Families:

• Experienced pediatric oncologists with global exposure
• Access to advanced surgical and ICU care for children
• Use of global treatment protocols (SIOP, COG)
• Availability of genetic testing (DICER1 mutation) and counseling
• Cost-effective treatment with full international support services (visa, travel, accommodation)
• No waiting time for diagnostics or surgery

Why choose Dr. Ankur Bahl for pediatric cancer care?

Dr. Ankur Bahl is a senior oncologist with extensive experience in treating rare pediatric tumors, including PPB. He collaborates with top pediatric thoracic surgeons, pathologists, and genetic counselors to ensure comprehensive care.

Dr. Bahl’s Strengths:

• 18+ years of oncology practice
• Expertise in childhood solid tumors and hereditary cancers
• Personalized care plans tailored for foreign families
• Offers virtual consultations and post-treatment tele-follow-ups
• Fluent coordination with global referral centers

What devices and technologies are used for PPB treatment in India?

India's leading pediatric oncology centers are equipped with cutting-edge devices and pediatric-friendly environments.

Medical Technology & Infrastructure:

• High-resolution CT and MRI scanners for pediatric imaging
• Thoracoscopic (minimally invasive) surgical equipment
• Pediatric intensive care units (PICU) with trained staff
• Laminar flow operating theaters for infection control
• Onco-pharmacy support for weight-based chemo dosing
• Genetic labs offering DICER1 mutation testing

What is the cost of treating PPB in India?

India offers one of the most affordable packages for high-quality pediatric cancer treatment worldwide.

Detailed Cost Breakdown (USD):

How does the cost in India compare to other countries?

India is significantly more affordable than most Western and Southeast Asian countries, without compromising quality or outcomes.

India’s cost advantage is particularly important for families managing complex, multi-step treatments like surgery + chemotherapy + long-term follow-up.

What is the treatment process and timeline for foreign patients?

India offers a streamlined treatment pathway tailored for international families:

Typical Timeline:

Week 1: Arrival, pediatric assessment, imaging, biopsy

Week 2: Surgery (lobectomy or tumor removal)

Week 3–8: Chemotherapy cycles every 2–3 weeks (outpatient or short admissions)

Week 9+: Recovery, discharge, and follow-up planning

Follow-Up: Online telemedicine and shared care with home country physician

Hospitals provide child-friendly accommodations and play areas to help reduce emotional stress during hospital stays.

What are the long-term outcomes and follow-up needs?

Outcomes for PPB depend significantly on the tumor type and timing of diagnosis.

Prognosis by Type:

Type I: >90% survival with early surgery

Type II: 70–80% survival with surgery + chemotherapy

Type III: 50–70% with aggressive multimodal therapy

Follow-Up Includes:

• Chest X-ray or CT scans every 3–6 months for 2 years, then annually
• Pulmonary function tests (especially post-lobectomy)
• Monitoring for tumor recurrence or secondary malignancies
• DICER1-positive patients may need screening for associated tumors

What are the advantages of early treatment in India?

Timely treatment can prevent tumor progression, reduce complications, and improve survival—especially in infants and toddlers.

Benefits of Early Intervention:

• Increases chance of complete surgical removal
• Avoids need for radiation (which is riskier in young children)
• Reduces long-term lung damage
• Improves quality of life with faster recovery
• Enables earlier genetic counseling and family planning

What documentation is needed for international families?

To ensure a smooth and timely medical travel experience, please prepare the following documents:

Required Medical Documents:

• Valid passport (child and parent/guardian)
• Medical visa (facilitated by hospital invitation letter)
• All past medical records, imaging reports (X-rays, CT, biopsy)
• Child’s immunization history
• Allergy list and prior medication details
• Parental consent and identification

How to start treatment with Dr. Ankur Bahl in India?

Dr. Ankur Bahl’s team offers a simple, fully coordinated path for international families to begin treatment quickly and confidently.

5 Simple Steps:

• Email or upload reports for preliminary review
• Schedule a video consultation with Dr. Bahl
• Receive a personalized treatment plan and cost estimate
• Get a visa invitation letter for expedited approval
• Travel to India and begin treatment with zero wait time

Patient coordinators help with airport pickups, translation, hotel stays, and dietary needs for young children.

Final Summary and Call to Action

Pleuropulmonary Blastoma (PPB) is a rare but potentially curable childhood cancer when diagnosed early and managed with precision. India offers a global advantage through:

• Affordable and high-quality care
• Pediatric-focused oncology teams
• Genetic diagnostics and full-family counseling
• Seamless services for international patients

With Dr. Ankur Bahl’s expert care, your child receives the most updated, compassionate, and personalized treatment plan available in Asia—backed by international protocols and complete post-treatment monitoring.

Ready to Begin?

Share your child’s reports now and speak directly with Dr. Bahl to plan the next steps toward safe, effective, and affordable treatment in India